Lorelei Lee is a beautiful showgirl engaged to be married to the wealthy Gus Esmond, much to the disapproval of Gus' rich father, Esmond Sr., who thinks that Lorelei is just after his money. When Lorelei goes on a cruise accompanied only by her best friend, Dorothy Shaw, Esmond Sr. hires Ernie Malone, a private detective, to follow her and report any questionable behavior that would disqualify her from the marriage.

An inventor makes contact with Mars via television. The film is notable for using the 3-D process called Teleview, similar to today's alternating frame 3-D systems. Shown in 3-D only at the Selwyn Theater in New York City, it was previewed as Mars Calling at a trade and press screening on 13 October 1922, premiered as M.A.R.S. on 27 December 1922, and ran through 20 January 1923. A 2-D version was distributed as Radio-Mania in 1923–1924.