Richard Kimble is falsely convicted of his wife's murder and given the death penalty. En route to death row, Kimble's train derails and crashes, allowing him to escape and begin a cross-country search for the real killer, a "one-armed man". At the same time, Dr. Kimble is hounded by the authorities, most notably dogged by Police Lieutenant Philip Gerard.

The cases of master criminal defense attorney Perry Mason and his staff who handled the most difficult of cases in the aid of the innocent.

In 1927 Hollywood, a silent film production company and cast make a difficult transition to sound.

A World War I widow loses her only child and spends the rest of her life as a children's nurse.