A precedent-setting comedy-drama special in which a salesman (Bob Newhart) and a sexologist (Jill St. John) have misadventures with plot development determined by the votes of the studio audience.

A small town is corrupted when two orphan girls, Penny and Pat arrive to live with their uncle. They soon meet up with a lesbian cousin, her moronic large cousin Aubrey, and their uncle who is as horny as a hardware store man. They scandalize everyone for having affairs with everyone like the motorbike gang, their uncle, their cousin, and the son of a religious preacher. When a gang member ends up being killed by a dose of LSD given by Penny, his homosexual lover revenges on her in a way you will not forget.