It is 1889, New Mexico. The gold rush is over and most of the prospectors have moved on. In the middle of nowhere stands a crumbling Antebellum mansion - a bordello that has seen better days. Enoch, the inept pimp, owes a considerable amount of money to the town's psychopathic Sheriff. Money is tight: business is down and the five-woman in the house are tearing each other apart. The only thing they can agree on is their love for Angel, a seven-year-old child whose mother died in childbirth.

In 2019, a medical company known as Coil Industries begins human trials of the controversial Amortal program. Aimed to have their cells replaced by self-replicating nanites, the two candidates, Jordan and Cass experience how becoming next stage of human evolution will affect them and others.

Two young women survive a vicious attack and begin to see themselves differently, believing they might be werewolves.

Last minute anxiety threatens to ruin a young gay couple's first threesome together.

Taking all that was great from the first instalment, the movie aims to be a wilder, leaner, faster-paced and even more entertaining anthology this time around, with a new crop of award-winning, visionary filmmakers from around the globe.

An intricate story unfolds when an undercover agent is interrogated by two detectives looking to solve the murder of their colleague.