Sara, a flight attendant in her thirties, takes desperate measures when she starts to believe her ex-boyfriend might kidnap her son.

A group of women, including Skipper, the wealthy young Jennifer and the domineering Nan, journey from the United States to South America in hopes of easily adopting children. Unfortunately, their plans are complicated by local laws that require the women to live in the foreign nation for an extended period before they can take in orphaned kids. While stuck in another country, the women bond as they share their aspirations and anxieties.

A fatalistic car crash in Mexico city sets off a chain of events in the lives of three people: a supermodel, a young man wanting to run off with his sister-in-law, and a homeless man. Their lives are catapulted into unforeseen situations instigated by the seemingly inconsequential destiny of a dog.