Aspiring architect Tom Thompson is told by mysterious Ruth Abernathy that his best friend, "Bill," has taken his own life. Except that Tom has never met Bill and neither have his incredulous friends. So when Tom foolishly agrees to give the eulogy at Bill's funeral, it sets him on a collision course with Ruth -- who is revealed to be Bill's oversexed mother -- and Julie DeMarco, the longtime crush Tom hasn't seen since they were teens.

Single mom Dottie Ingels sells cosmetics in a department store, but she dreams of being a comedian. When she inherits some money, she takes the chance and moves with her two children Erica and Opel to New York to perform in small bars. Soon her agent Arnold Moss makes her famous, but while she travels all over USA, her children stay home lonely.

An ophthalmologist's mistress threatens to reveal their affair to his wife, while a married documentary filmmaker is infatuated by another woman.