Joseph "Doc" Frail is a doctor with a past he's trying to outrun. While in Montana, he comes across a mining camp with a hanging tree and rescues a man named Rune from the noose. With Rune as his servant, Frail decides to settle down, and he takes over as town doctor. He meets Elizabeth, who is suffering from shock, and the two soon fall in love. But when Elizabeth is attacked, Frail's attempt to help her lands them both in trouble.

In 1859, idealist John Wickliff Shawnessey, a resident of Raintree County, Indiana, is distracted from his high school sweetheart Nell Gaither by Susanna Drake, a rich New Orleans girl. This love triangle is further complicated by the American Civil War, and dark family history.

Two brothers discharged from the Confederate Army join a businessman for a cattle drive from Texas to Montana where they run into raiding Jayhawkers, angry Sioux, rough terrain and bad weather.

Two former enemies find themselves together on a cattle drive and fighting marauding Apaches and Mexican bandits.

Former buffalo hunter and entrepreneur Wyatt Earp arrives in the lawless cattle town of Wichita Kansas. His skill as a gun-fighter makes him a perfect candidate for Marshal, but he refuses the job until he feels morally obligated to bring law and order to this wild town.

A formula brawling-buddies western where one goes bad and then returns to the fold. Pete Menlo owns some gold claims in Nevada where he is joined by his old friend Andy Martin. Crooked mine-owner Bannon wants to merge their interests so they can create a monopoly but is turned down. Pete is interested in "Nevada" Wray, daughter of mine-owner "Jackpot" Wray, but she has eyes only for Andy. The rejected Pete joins forces with Bannon and they learn that, because of location, "Jackpot" Wray may be the owner of all the gold in the respective veins. Bannon and his men try to get rid of Andy.

Cattle baron Matt Devereaux raids a copper smelter that is polluting his water, then divides his property among his sons. Son Joe takes responsibility for the raid and gets three years in prison. Matt dies from a stroke partly caused by his rebellious sons and when Joe gets out he plans revenge.

An itinerant farmer and his young son help a heart-of-gold saloon singer search for her estranged husband.

In 1896, Jeff Webster sees the start of the Klondike gold rush as a golden opportunity to make a fortune in beef...and woe betide anyone standing in his way! He drives a cattle herd from Wyoming to Seattle, by ship to Skagway, and (after a delay caused by larcenous town boss Gannon) through the mountains to Dawson. There, he and his partner Ben Tatum get into the gold business themselves. Two lovely women fall for misanthropic Jeff, but he believes in every-man-for-himself, turning his back on growing lawlessness...until it finally strikes home.