The Hugo's Brain is a French documentary-drama about autism. The documentary crosses authentic autistic stories with a fiction story about the life of an autistic (Hugo), from childhood to adulthood, portraying his difficulties and his handicap.

Clem follows the life of a young teenager, Clémentine, who becomes a mother at the age of sixteen, at the centre of tensions between her parents and Julien, the father of her child Valentin. It deals with the problems of teenage life and that of a mother with a strong personality.