When narcotics detective Ike Walters visits his former partner Stetson Avery in rural Greentown, he inexplicably finds himself the target in a deadly game of deceit. Befriended by the alluring yet suspicious Renee Dupa, Ike discovers that his life has been placed on the line and that nothing is what it seems.

As America's stock of athletic young men is depleted during World War II, a professional all-female baseball league springs up in the Midwest, funded by publicity-hungry candy maker Walter Harvey. Competitive sisters Dottie Hinson and Kit Keller spar with each other, scout Ernie Capadino and grumpy has-been coach Jimmy Dugan on their way to fame.