When a deadly assassin hijacks a passenger train, he threatens to detonate a deadly can of poison that can wipe out an entire city, if he isn't given a 25 million dollar Ransom. While the cops are attempting to thwart the madman, they decide to call Former DEA agent Paul Blake (Antonio Sabato, Jr) the one man who can possibly stop the fiendish plot.

Early 20th-century adventurers find themselves fighting for survival after their hot-air balloon crashes into a remote part of the Amazon, stranding them on a prehistoric plateau.