Los Angeles, 1949. Ruthless, Brooklyn-born mob king Mickey Cohen runs the show in this town, reaping the ill-gotten gains from the drugs, the guns, the prostitutes and — if he has his way — every wire bet placed west of Chicago. And he does it all with the protection of not only his own paid goons, but also the police and the politicians who are under his control. It’s enough to intimidate even the bravest, street-hardened cop… except, perhaps, for the small, secret crew of LAPD outsiders led by Sgt. John O’Mara and Jerry Wooters who come together to try to tear Cohen’s world apart.

A television reporter and her cameraman are trapped inside a building quarantined by the CDC after the outbreak of a mysterious virus which turns humans into bloodthirsty killers.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.