Roxy and Lily survive the night after botched plastic surgery.

Seventeen year old Tanya's plans for a carefree summer are derailed when her stressed-to-the-limit mom takes off for a wellness retreat and puts Tanya and her three siblings in the charge of a crotchety (and racist) old babysitter. The babysitter’s sudden death leaves the kids short on cash and reluctant to pull mom prematurely out of her much-needed R&R, so Tanya is forced to get a job. Posing as an adult, she gets a gig as the executive assistant at a fashion company and overnight is thrust into the world of adulthood and parenting.

Unpopular best friends PJ and Josie start a high school self-defense club to meet girls and lose their virginity. They soon find themselves in over their heads when the most popular students start beating each other up in the name of self-defense.

After teenage Ben comes to the realization that his stage 4 testicular cancer is terminal, he decides to throw a "practice funeral" as one final hurrah before the end of his young life.

A tough, brilliant senior resident guides an idealistic young doctor through his first day, pulling back the curtain on what really happens, both good and bad, in modern-day medicine.