Rabbi Avram arrives in Philadelphia from Poland en route to San Francisco where he will be a congregation's new rabbi. An innocent and inexperienced traveller, he is tricked by con men to pay for the trip to go west, then they leave him and his belongings scattered along a deserted road. He is befriended by a stranger, Tommy, who is a bank robber and have many adventures during their journey.

The O'Toole Brothers are Eastern con men, exceptionally good at talking their way out of tight situations. When they ride into Molybdenum, Colorado, not suspecting the riches beneath the streets, they turn the sleepy mining town upside-down for their search for the gold. High-spirited hijinks ensue, with the brothers involved in everything from stolen gambling equipment to a "belchin', cussin' and spittin' " contest.