In a massive, mysterious chamber, fifty strangers awaken to find themselves trapped with no memory of how they got there. Organized in an inward-facing circle and unable to move, they quickly learn that every two minutes, one of them must die…executed by a strange device in the center of the room.

Obstetrician/gynecologist Mindy Lahiri tries to balance her personal and professional life, surrounded by quirky co-workers in a small medical practice in New York City.