In this musical-comedy, Dean Martin plays an American hotel mogul who becomes smitten with a young Italian woman (Anna Maria Alberghetti) when buying a hotel in Rome. To marry this gal, he has to get her three older sisters married off.

Cuban Bandleader Ricky Ricardo would be happy if his wife Lucy would just be a housewife. Instead she tries constantly to perform at the Tropicana where he works, and make life comically frantic in the apartment building they share with landlords Fred and Ethel Mertz, who also happen to be their best friends.