Amid a future war between the human race and the forces of artificial intelligence, a hardened ex-special forces agent grieving the disappearance of his wife, is recruited to hunt down and kill the Creator, the elusive architect of advanced AI who has developed a mysterious weapon with the power to end the war—and mankind itself.

Cruz Manuelos, a rough-around-the-edges but passionate young Marine, is recruited to join the CIA’s Lioness Engagement Team to help bring down a terrorist organization from within. Joe, the station chief of the Lioness program, is tasked with training, managing and leading her female undercover operatives.

This mystery-of-the-week series follows Charlie Cale, who has an extraordinary ability to determine when someone is lying. She hits the road with her Plymouth Barracuda and with every stop encounters a new cast of characters and strange crimes she can’t help but solve.

A former Marine out to punish the criminals responsible for his family's murder finds himself ensnared in a military conspiracy.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.