Herbert West is totally out of control on campus, sticking his glowing green reagent into every corpse he can find!

The malevolent inter-dimensional machine is still channeling monsters and blowing minds, but this time things get even more complicated with the arrival of mad med student Herbert West and his dreaded reagent!

Visionary Miskatonic University student Crawford Tillinghast follows in his late father's footsteps and becomes obsessed with completing work on the Resonator, an inter-dimensional device that opens doorways to other worlds.

Two best friends with a strained relationship experience unusual occurrences during their stay at a remote ranch, leading them to fight for their lives against the deceptively charming ranch owner and his late wife.