An examination of the consequences of vaccine hesitancy and denial. It's a war anti-vax activists have been fighting for a decade. And COVID-19 is what they practiced for: A national conversation about vaccine safety.

The film interweaves the personal accounts of polio survivors with the story of an ardent crusader who tirelessly fought on their behalf while scientists raced to eradicate this dreaded disease. Based in part on the Pulitzer Prize-winning book Polio: An American Story by David Oshinsky, Features interviews with historians, scientists, polio survivors, and the only surviving scientist from the core research team that developed the Salk vaccine, Julius Youngner.