10 years after Dexter went missing in the eye of Hurricane Laura, we find him living under an assumed name in the small town of Iron Lake, New York. Dexter may be embracing his new life, but in the wake of unexpected events in this close-knit community, his Dark Passenger beckons.

Alice is young hearing-impaired girl who, after a supposed visitation from the Virgin Mary, is inexplicably able to hear, speak and heal the sick. As word spreads and people from near and far flock to witness her miracles, a disgraced journalist hoping to revive his career visits the small New England town to investigate. When terrifying events begin to happen all around, he starts to question if these phenomena are the works of the Virgin Mary or something much more sinister.

A young Victoria "Vic" McQueen discovers she has the power to unlock portals that help her find lost objects. As she delves further into this hidden universe, she encounters many other "inscape travelers" - some benevolent, and some who have been corrupted by their power. When Vic encounters Charlie Manx, an immortal who stays that way by feeding off of the souls of children, she makes a sworn enemy of Manx.