1988: After an accident at a research lab, the population of Los Angeles is mutating into ferocious zombies eager to feed on the living. Two women take refuge in a museum but fall right into the hands of a pair of homicidal ex-convicts, who kidnap and torment the women as the undead hoard grows larger and stronger.

15 years after the original events, Doll Restoration artist Stephanie is followed by Charlie Crandall to her new home in Southern California for a final game of cat and mouse.