Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

Chuck Norris stars as martial arts extraordinaire Jake Fallon, who, after the death of his brother and sister-in-law, adopts (and trains) his orphaned nephew. Logan (Eddie Cibrian, TV's Invasion). After fifteen years of careful instruction, Logan is determined to avenge his parents Death... And, he'll need Uncle Jake's help to do it.

Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.