Aging King George III of England is exhibiting signs of madness, a problem little understood in 1788. As the monarch alternates between bouts of confusion and near-violent outbursts of temper, his hapless doctors attempt the ineffectual cures of the day. Meanwhile, Queen Charlotte and Prime Minister William Pitt the Younger attempt to prevent the king's political enemies, led by the Prince of Wales, from usurping the throne.

The Upper Hand is a British television sitcom, produced by Central Independent Television and Columbia Pictures Television and broadcast by ITV from 1990 to 1996. The programme was adapted from the American sitcom Who's the Boss?. As in the former series, an affluent single woman, raising a son with the help of her mother, hires a housekeeper only to have a man apply for the job.