Mannix is an American television detective series that ran from 1967 through 1975 on CBS. Created by Richard Levinson and William Link and developed by executive producer Bruce Geller, the title character, Joe Mannix, is a private investigator. He is played by Mike Connors. Mannix was the last series produced by Desilu Productions.

During the Korean War, Italian nurse Virna Lisi falls in love with two American fliers, Tony Curtis and George C. Scott. Lisi marries Curtis after he convinces her that Scott has been killed in a plane crash. She soon discovers Scott is alive, but remains happily married to Curtis until Scott re-enters their lives 14 years later.

A wagon train heads for Denver with a cargo of whisky for the miners. Chaos ensues as the Temperance League, the US cavalry, the miners and the local Indians all try to take control of the valuable cargo.