Brad Williams is only the second person ever studied by neurologists for the newly-identified syndrome called "hyperthymesia", an extremely detailed form of autobiographical memory for events both global and personal, monumental and trivial. UNFORGETTABLE follows Brad's adventures as his rare mental gifts vault him from small-town anonymity to sudden mid-life notoriety.

On the eve of 1987's Second National March on Washington for Lesbian and Gay Rights, surviving families and friends of people who have died of AIDS prepare panels to be added to a large-scale memorial quilt project. Drawing from the sea of names memorialized, director Robert Epstein focuses on the lives of six people. Alongside the intimate profiles offered, through news footage and interviews, Epstein puts the AIDS crisis in the larger context of social and government response to the disease.