Faced with finding a kidney donor, newly divorced dad Drew is at the end of his rope when he runs into Gina, a rough-around-the edges woman from his past who volunteers her own. Together they form an unlikely bond and begin a journey that will change both of their lives.

The murderous, backwoods Firefly family take to the road to escape the vengeful Sheriff Wydell, who is not afraid of being as ruthless as his target.