Four best friends take their book club to Italy for the fun girls' trip they never had. When things go off the rails and secrets are revealed, their relaxing vacation turns into a once-in-a-lifetime cross-country adventure.

After two childhood friends experience a vision together; the unstable teens flee to the West Coast using their intuition as guidance, but emotions, secrets, and acts of insanity cripple their journey to ever grasping 'destiny.'