Pot growers Ben and Chon face off against the Mexican drug cartel who kidnapped their shared girlfriend.

Entirely made in California, the film brings together 30 American and European actors in an epic which crosses the mythical territories of that cinematic land from Zabriskie Point to Mulholland Drive. California is revisited through the movie memories incarnated by the very presence of famous actors and actresses. "The American Tetralogy" is a way of staging reality which questions the fictional nature of the movies.