When a presidential candidate dies unexpectedly in the middle of the campaign, the Democratic party unexpectedly picks a Washington, D.C. alderman as his replacement.

A secretary is found dead in a White House bathroom during an international crisis, and Detective Harlan Regis is in charge of the investigation. Despite resistance from the Secret Service, Regis partners with agent Nina Chance. As political tensions rise, they learn that the crime could be part of an elaborate cover-up. Framed as traitors, the pair, plus Regis' partner, break into the White House in order to expose the true culprit.

Veteran Secret Service agent Frank Horrigan is a man haunted by his failure to save President Kennedy while serving protection detail in Dallas. Thirty years later, a man calling himself "Booth" threatens the life of the current President, forcing Horrigan to come back to protection detail to confront the ghosts from his past.