Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.

An undercover cop lets his job get personal while on an underground assignment.

Anthology series of composed of distinct story episodes, sometimes with a plot twist at the end, with occasional recurring story elements that were often tied together during season-finale clip shows.