The nerds are now in control of the university, as a result of Lewis Skolnick and the rest's actions in the two previous movies. A new generation of sportsmen arrive, however, determined on winning the school back. The principle, himself an ex-nerd fighter, helps them, and the nerds return to suppression. Harold Skolnick needs help from his uncle Lewis, the hero of the first two movies. Lewis, however, are not too proud of his nerd past, and won't reveal any of it, much less help his nephew. However, his wife makes him change his mind, and with help from his friends from the first two movies, they start the fight to win the school back, using classic nerd tricks.

Theorizing that one could time travel within his own lifetime, Dr. Sam Beckett stepped into the Quantum Leap accelerator and vanished... He woke to find himself trapped in the past, facing mirror images that were not his own and driven by an unknown force to change history for the better. His only guide on this journey is Al, an observer from his own time, who appears in the form of a hologram that only Sam can see and hear. And so Dr. Beckett finds himself leaping from life to life, striving to put right what once went wrong and hoping each time that his next leap will be the leap home.