With the help of student assistant Boris and stolen university equipment, Dr. Harry Wolper plans to clone his dead wife. But then he meets Meli, an egg donor for his experiment, and they fall in love. Faced with choosing between his deceased wife and Meli, Dr. Wolper sees his situation in a new light when Boris' own new love, Barbara, falls into a coma. Meanwhile, another professor tries shutting down the cloning project.

After being duped and going bankrupt, model Maddie is convinced by David to become a partner in a detective agency. Together they solve various cases, while getting comfortable with each other.

After deciding he needs to do something meaningful with his life, high school wrestler Louden Swain sets out on a mission to drop weight and challenge the area's undefeated champion, which creates problems with his teammates and health. Matters are complicated further when Louden's father takes in an attractive female drifter who's on her way to San Francisco.