On the edge of revolutionary change at their all boys private high school, three friends set out to have one last great weekend while dodging authority, love affairs and violent foes in the longest weekend of their lives.

An emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room.