As an epidemic of a lethal airborne virus - that kills within days - rapidly grows, the worldwide medical community races to find a cure and control the panic that spreads faster than the virus itself.

A man's journey to win back his former love forces him to confront a past of emotional immaturity, drinking, and thwarted artistic ambitions.

In Manhattan, the aspirant writer Jabez Stone is a complete loser: he is not able to sell his novels, he lives in a lousy apartment and he does not have success with women. When one of his friends Julius Jenson sells his novel for US$ 190,000.00 to an editor, Jabez fells envy and promises to sell his soul to the devil for success and accidentally kills a woman with his typing machine. The Devil knocks on his door, fixes the situation and seals a contract with Jabez. His low quality novels have bad reviews but become best-sellers; Jabez enriches; has success with women, but has no time for his friends. Jabez meets with the publisher Daniel Webster who offers him a chance to break the contract with the devil.

Underachieving, overweight kindergarten teacher Dex finds a woman who forces him to reexamine his Zen-like system of seduction.

Shane, a Jersey boy with big dreams, crosses the river in hopes of finding a more exciting life at Studio 54. When Steve Rubell, the mastermind behind the infamous disco, plucks Shane from the sea of faces clamoring to get inside his club, Shane not only gets his foot in the door, but lands a coveted job behind the bar – and a front-row seat at the most legendary party on the planet.