Opposite Lives tells the story of Miguel (Leo Rosa), a young rich man of a traditional family, and Joana (Maytê Piragibe), a student and tourist guide who lives in a slum. Although dating an elegant and rich fashion designer, Erínia (Lavínia Vlasak), Miguel and Joana fall in love for each other and they decide to get married.

Brazilian version of the reality game show in which a group of houseguests live together 24 hours a day, isolated from the outside world but under constant surveillance with no privacy. Each week a guest is voted out of the house until only the winner remains.