Nemo Bandera (Amendola) is one of the most influential businessmen in Puglia. His assets originate from illicit trafficking whose proceeds were invested in Deep Sea, the profitable company inherited from his father-in-law and used as a cover. One day, all of Nemo’s certainties collapse: he discovers that he is suffering from Alzheimer’s. Shocked by the news, he decides to hide it while choosing who will inherit his empire.

In a neighbourhood on the outskirts of Taranto, high upon the rooftops framed by the Ilva steel factory, we meet Tonino a.k.a. “Barboncino” (poodle). Tonino has just committed a robbery and, in a moment of foolishness, fled from his accomplices, taking the entire loot for himself. He escapes upward, clambering from roof to roof, until he can go no further and must take refuge in an old water tank. Here he finds Renato, a strange and eccentric man who believes he is an American Indian from the Sioux tribe. Trapped with no other choice, Tonino is forced to team up with Renato. A strange and crazy friendship is formed, and Tonino learns to see things from a very different perspective.