Robert McCall finds himself at home in Southern Italy but he discovers his friends are under the control of local crime bosses. As events turn deadly, McCall knows what he has to do: become his friends' protector by taking on the mafia.

Set in the multi-ethnic communities on the outskirts of Milan, three teenagers grow up and deal with love, generational conflicts, female emancipation and, above all, power struggles.

Simone Segre, a renowned surgeon of Jewish origins, lives in a city in the north-east of Italy. A quiet life, an elegant apartment and no connection with his past. One day he finds himself assisting a man victim of a hit and run accident. But when he discovers a nazi tattoo on his chest, Simone abandons him to his destiny. Filled with guilt, he ends up tracing the man’s family: Marica, the eldest daughter; Marcello, a teenager plagued with racial hate; and little Paolo. The night will come when Marica knocks at Simone’s door and unknowingly asks for payback.

Alice is a clumsy and passionate coroner resident. She fights between life and love complexities. Even tough she still has a lot to learn, she has a special quality: empathy with the victims that leads her to have crucial intuition in the cases that she works on.