The townsfolk are set on lynching an accused killer held in the town lockup. But US Marshal Johnny Reno stands in their way.

Various stage coach passengers and outlaws travelling through Indian country are forced to join forces against the Apaches.

Passengers on a ship traveling from Mexico to Europe in the 1930s represent society at large in that era. The crew is German, including the ship's Dr. Schumann, who falls in love with one of the passengers, La Condesa. A young American woman, Jenny, is traveling with the man she loves, David. Jenny is fascinated and puzzled by just who some of the other passengers are.

A prominent Cuban landowner flees to Miami with his anti-Castro activist younger son, where he learns that his elder son is working to sabotage the Bay of Pigs invasion.