In the future, medical technology has advanced to the point where people can buy artificial organs to extend their lives. But if they default on payments, an organization known as the Union sends agents to repossess the organs. Remy is one of the best agents in the business, but when he becomes the recipient of an artificial heart, he finds himself in the same dire straits as his many victims.

Todd's life takes a turn when his friendship with a homosexual causes everyone in his life to start questioning his sexuality.

Rose, a desperate mother takes her adopted daughter, Sharon, to the town of Silent Hill in an attempt to cure her of her ailment. After a violent car crash, Sharon disappears and Rose begins a desperate search to get her back. She descends into the center of the twisted reality of a town's terrible secret. Pursued by grotesquely deformed creatures and townspeople stuck in permanent purgatory, Rose begins to uncover the truth behind the apocalyptic disaster that burned the town 30 years earlier.