Sylvia Stickles runs a convenience store with her husband and mother-in-law. One day, Sylvia is hit on the head and transforms from an uptight prude to a sex-crazed lunatic. As she goes on a rampage through town, Sylvia attracts the attention of Ray Ray, a sexual healer and tow truck driver in search of the world's greatest orgasm. Their sexual revolution, however, causes a class war in their tiny Baltimore community.

A detective is assigned to transporting a homeless man to a psyche ward after he was caught tampering with a radio tower to block alien communication to the moon. The man claims he must kill a big-time media mogul whom he believes is an alien leading the extermination of the human race. The detective must decide to either stop this man's insane mission, or to believe him in order to save the planet from the coming invasion.