Father O'Malley is sent to St. Mary's, a run-down parochial school on the verge of condemnation. He and Sister Benedict work together in an attempt to save the school, though their differing methods often lead to good-natured disagreements.

Edinburgh, 1831. Among those who undertake the illegal trade of grave robbery is Gray, ostensibly a cab driver. Formerly a medical student convicted of grave robbery, Gray holds a grudge against Dr. MacFarlane who had escaped detection and punishment.

After breaking up with her fiancé, a gym teacher returns to work at a women's college, but a legal loophole allows him to enroll as one of her students.