After a Black Friday riot ends in tragedy, a mysterious Thanksgiving-inspired killer terrorizes Plymouth, Massachusetts - the birthplace of the holiday. Picking off residents one by one, what begins as random revenge killings are soon revealed to be part of a larger, sinister holiday plan.

When Rosie's Mom dies she needs somewhere to live. The only relative to be found is Fred (Frédérique) - tough, street-smart, and currently working in a sex shop, though not for long. Her two best friends - who refuse to be restricted by gender - are Flo and Mo; they are loyal to the core and Fred's own chosen family. When the adult store goes up in flames the colourful foursome must do what they have to to survive. A quirky family of fringe dwellers is born!