Belgian sleuth Hercule Poirot's Egyptian vacation aboard a glamorous river steamer turns into a terrifying search for a murderer when a picture-perfect couple's idyllic honeymoon is tragically cut short.

Joseph and Lindsey are a famous, talented, and wealthy young couple who reside in their hometown of Plotagon City, and have earned the title of Plotagon City's most famous and richest couple. They have appeared in films and television shows, including their favorite, Love Birds. Joseph's siblings and friends support him and Lindsey's relationship; however, Joseph's incarcerated and maniacal ex-girlfriend Beryl opposes the relationship.