Heather is an exotic dancer who has become a vampire and works at a nightclub named Vamps, managed by her fiancé Seamus, a defrocked priest. They learn that they have made a powerful enemy in Elizabeth, another comely female vampire whose sister was killed by the denizens of Vamps years before. Elizabeth is eager to get revenge against Heather and her fellow vampire strippers, especially since Heather and Seamus could possibly bring about the Prophesy of the Redeemer, which would bring an end to vampires once and for all.

Shakespeare's plays were intended not to be performed by men only, it turns out, but rather by buxom young women in various stages of undress. Such is the premise of this low-budget vehicle which alternates between scenes of women stripping while performing scenes from the Bard's works and mock interviews with the cast and crew.