Heather is an exotic dancer who has become a vampire and works at a nightclub named Vamps, managed by her fiancé Seamus, a defrocked priest. They learn that they have made a powerful enemy in Elizabeth, another comely female vampire whose sister was killed by the denizens of Vamps years before. Elizabeth is eager to get revenge against Heather and her fellow vampire strippers, especially since Heather and Seamus could possibly bring about the Prophesy of the Redeemer, which would bring an end to vampires once and for all.

A public relations firm is really a front for a devil-worshiping cult that kidnaps young models to sacrifice to the devil. A reporter stumbles onto their operation.