Eddie Garrick is a good-hearted man who has lost his belief in the wonder of Christmas. While spending time with his nine-year-old daughter Charlotte on Christmas Eve, he befriends a mysterious man in a red suit named Nick.

Despite initially starting out in wedded bliss, devoted wife Candice and her manipulative husband, Ken, end up at odds, so much so that he hires a hitman to kill her and their unborn child. Candice finds herself embroiled in the fight of her life.

A tough, brilliant senior resident guides an idealistic young doctor through his first day, pulling back the curtain on what really happens, both good and bad, in modern-day medicine.