Opposites make for great comedy in the life-long friendship of comedy legends Bob Newhart and Don Rickles by Judd Apatow.

The documentary consists of tape of Don's show (never been filmed before), interviews with Don's contemporaries, (Steve Lawrence, Bob Newhart, Debbie Reynolds, etc.), established comedians (Billy Crystal, Rosanna Barr, Robin Williams, Chris Rock, etc.) and young comedians (Jeff Atoll, Jimmy Kimmel, Sarah Silverman, etc.).