Set in Chicago, the show follows the kid-friendly misadventures of two high-school friends who are always scheming and dreaming. Kenan, who works at a grocery store, constantly devises crazy plans to strike it rich, while orange-soda-loving buddy Kel is always dragged along for the ride despite his track record for messing things up.

Junior and his father, Ben, move from Cold River to Mortville. Junior becomes threatened by Ben's desire to date again and find a new mother for Junior, and sabotages each of his dates.