Manhattan, 1996. All mental hospitals must cut their patient load by a third, and LaRue (Will Keenan) is sent out onto the streets with "chronic reading syndrome". He ends up at the Love Hotel (where most of the inmates are being held), and falls in love with a mute girl who's obsessive mother dominates her life. To top it all off, LaRue is given a roommate with Tourette's syndrome and is chased by a prehistoric worm that inhabits peoples bodies and mutates them.

A divorcee decides to fight back after her hopes of gaining a promotion are dashed by her rejection of the advances of her boss, and it is only after he actually attacks her that her company and her union take notice.