An ultraconservative police officer suffers a debilitating stroke and is assigned to a rehabilitative program that includes singing lessons - with the drag queen next door.

Small rocks fall from the sky which, when touched, trigger a latent virus that has always existed in humans and begins mutating them into an alien species. Taking advantage of its hive mentality, the aliens are absolutely dedicated to transforming every human on Earth and do so with alarming swiftness. Only a small group of humans remain who have the medical knowledge to devise antibodies to reverse the effects of the virus.

The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.