Five friends struggling in their lives head to the desert for a girls weekend of restorative scream therapy. Their vacation takes a sharp turn when they cross paths with a cult of incels who are on a very pressing human sacrifice deadline.

In this musical comedy, optimistic high school teacher Will Schuester tries to refuel his own passion while reinventing the high school's glee club and challenging a group of outcasts to realize their star potential as they strive to outshine their singing competition while navigating the cruel halls of McKinley High.